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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP16
All Species:
18.18
Human Site:
S412
Identified Species:
40
UniProt:
Q9BY84
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BY84
NP_085143.1
665
73102
S412
K
S
V
S
Y
S
A
S
M
A
A
S
L
H
G
Chimpanzee
Pan troglodytes
XP_520751
665
73101
S412
K
S
V
S
Y
S
A
S
M
A
A
S
L
H
G
Rhesus Macaque
Macaca mulatta
XP_001084619
665
73124
S412
K
S
V
S
Y
S
A
S
M
A
A
S
L
H
G
Dog
Lupus familis
XP_543810
663
72657
S409
K
S
V
S
Y
S
A
S
V
A
A
S
L
H
G
Cat
Felis silvestris
Mouse
Mus musculus
O09112
663
68829
D411
Y
A
P
S
R
R
P
D
F
P
G
P
P
D
P
Rat
Rattus norvegicus
NP_001100094
661
72804
S408
K
S
V
S
Y
S
A
S
V
A
A
S
L
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508628
481
51865
D229
E
T
I
L
P
W
L
D
R
S
V
E
F
I
E
Chicken
Gallus gallus
XP_428887
701
77250
V448
Y
S
A
A
S
S
C
V
T
A
S
V
Q
G
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998405
539
59053
F287
T
I
S
P
N
F
N
F
L
G
Q
L
L
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
E405
P
S
M
P
S
T
S
E
Q
G
T
S
S
G
T
Sea Urchin
Strong. purpuratus
XP_787378
916
99998
R615
S
V
G
F
Q
F
G
R
S
R
I
N
H
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
93
N.A.
44.2
90.5
N.A.
52.9
77.1
N.A.
54.5
N.A.
N.A.
N.A.
30.5
33.7
Protein Similarity:
100
99.5
99
95.7
N.A.
57.8
94.8
N.A.
60.5
83.4
N.A.
64.5
N.A.
N.A.
N.A.
46.1
47.6
P-Site Identity:
100
100
100
93.3
N.A.
6.6
93.3
N.A.
0
20
N.A.
6.6
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
100
N.A.
26.6
33.3
N.A.
13.3
N.A.
N.A.
N.A.
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
46
0
0
55
46
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
19
0
0
0
0
0
19
10
% D
% Glu:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
10
0
19
0
10
10
0
0
0
10
0
19
% F
% Gly:
0
0
10
0
0
0
10
0
0
19
10
0
0
19
46
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
46
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
10
0
10
0
0
10
55
0
0
% L
% Met:
0
0
10
0
0
0
0
0
28
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
10
0
10
19
10
0
10
0
0
10
0
10
10
10
10
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
10
10
0
10
10
10
0
0
0
0
0
% R
% Ser:
10
64
10
55
19
55
10
46
10
10
10
55
10
0
0
% S
% Thr:
10
10
0
0
0
10
0
0
10
0
10
0
0
0
10
% T
% Val:
0
10
46
0
0
0
0
10
19
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _